4ogy: Difference between revisions

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 <StructureSection load='4ogy' size='340' side='right'caption='[[4ogy]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4ogy]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OGY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OGY FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4ogy]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OGY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OGY FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2any|2any]], [[4ogx|4ogx]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ogy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ogy OCA], [https://pdbe.org/4ogy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ogy RCSB], [https://www.ebi.ac.uk/pdbsum/4ogy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ogy ProSAT]</span></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KLK3, KLKB1, KLKB1_HUMAN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Plasma_kallikrein Plasma kallikrein], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.34 3.4.21.34] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ogy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ogy OCA], [http://pdbe.org/4ogy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ogy RCSB], [http://www.ebi.ac.uk/pdbsum/4ogy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ogy ProSAT]</span></td></tr>
 </table>
-== Disease ==
-[[http://www.uniprot.org/uniprot/KLKB1_HUMAN KLKB1_HUMAN]] Defects in KLKB1 are the cause of prekallikrein deficiency (PKK deficiency) [MIM:[http://omim.org/entry/612423 612423]]; also known as Fletcher factor deficiency. This disorder is a blood coagulation defect.
 == Function ==
-[[http://www.uniprot.org/uniprot/KLKB1_HUMAN KLKB1_HUMAN]] The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
+[https://www.uniprot.org/uniprot/S6C4R2_HUMAN S6C4R2_HUMAN]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 25: / Line 20: @@
 ==See Also==
-*[[Kallikrein|Kallikrein]]
+*[[Kallikrein 3D structures|Kallikrein 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Plasma kallikrein]]
+[[Category: Abendroth J]]
-[[Category: Abendroth, J]]
+[[Category: Clifton MC]]
-[[Category: Clifton, M C]]
+[[Category: Edwards TE]]
-[[Category: Edwards, T E]]
+[[Category: Ladner R]]
-[[Category: Ladner, R]]
+[[Category: Nixon A]]
-[[Category: Nixon, A]]
-[[Category: Acute hereditary angioedema]]
-[[Category: Antibody]]
-[[Category: Blood]]
-[[Category: Bradykinin]]
-[[Category: C1-inh]]
-[[Category: Edema]]
-[[Category: Fab]]
-[[Category: Fletcher factor]]
-[[Category: Hae]]
-[[Category: Haw]]
-[[Category: Hereditary angioedema]]
-[[Category: Hmwk]]
-[[Category: Hydrolase-antibody complex]]
-[[Category: Kallikrein]]
-[[Category: Kininogenin]]
-[[Category: Plasma]]
-[[Category: Plasma kallikrein- mediated edema]]
-[[Category: Serine protease]]
-[[Category: Serpin c1-inhibitor]]