Flavodoxin: Difference between revisions

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*<scene name='41/413119/Cv/5'>Apo-Flavodoxin from Helicobacter pylori complexed with benzamidine and chloride ion</scene>.
*<scene name='41/413119/Cv/5'>Apo-Flavodoxin from Helicobacter pylori complexed with benzamidine and chloride ion</scene>.
*<scene name='41/413119/Cv/6'>Cl coordination site</scene>. Water molecules shown as red spheres.
*<scene name='41/413119/Cv/6'>Cl coordination site</scene>. Water molecules shown as red spheres.
 
 
== 3D Structures of Flavodoxin ==
[[Flavodoxin 3D structures]]
 
</StructureSection>
</StructureSection>


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**[[4heq]] - FDX-ox – ''Desulfovibrio gigas'' <br />
**[[4heq]] - FDX-ox – ''Desulfovibrio gigas'' <br />
**[[1ag9]] – EcFDX-ox<br />
**[[1ag9]] – EcFDX-ox<br />
**[[2mok]] – EcFDX-ox – NMR<br />
**[[2mt9]], [[2mtb]] – EcFDX-ox 2 – NMR<br />
**[[1flv]] – nFDX-ox<br />
**[[1flv]] – nFDX-ox<br />
**[[1xyy]], [[1j9g]], [[1c7f]], [[1akr]], [[1akt]], [[1akw]] – DvFDX-ox (mutant)<br />
**[[1xyy]], [[1j9g]], [[1c7f]], [[1akr]], [[1akt]], [[1akw]] – DvFDX-ox (mutant)<br />
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**[[5yob]], [[5yoc]], [[5yoe]], [[5yog]] - DvFDX-ox (mutant) <br />
**[[5yob]], [[5yoc]], [[5yoe]], [[5yog]] - DvFDX-ox (mutant) <br />
**[[5lji]] - SpFDX-ox  <br />
**[[5lji]] - SpFDX-ox  <br />
**[[6ohl]] - FnFDX-ox – ''Fusobacterium nucleatum''<br />
**[[6ohk]] - FnFDX-ox (mutant) <br />
**[[5wid]] – FDX-ox - ''Methanosarcina acetivorans''<br />


* FDX containing FMNH (semiquinone)  
* FDX containing FMNH (semiquinone)  


**[[2x2o]], [[2x2p]] – NrdI-sq – ''Bacillus cereus''<br />
**[[2x2o]], [[2x2p]], [[6fsg]], [[6fsi]], [[6ft1]], [[6gaq]] – NrdI-sq – ''Bacillus cereus''<br />
**[[3kaq]], [[3f90]] – DdFDX-sq <br />
**[[3kaq]], [[3f90]] – DdFDX-sq <br />
**[[1xt6]], [[1wsw]], [[1xyv]], [[1akv]], [[1wsb]] - DvFDX-sq (mutant)<br />
**[[1xt6]], [[1wsw]], [[1xyv]], [[1akv]], [[1wsb]] - DvFDX-sq (mutant)<br />

Revision as of 11:10, 3 July 2019


Flavodoxin (FDX) is a bacterial protein which contains flavin mononucleotide (FMN) or flavin adenine dinucleotide (FAD). It participates in nitrogen metabolism and reduces N2 to NH3 while changing from its oxidized quinone state FDX-ox via semiquinone FDX-sq to its reduced hydroquinone state FDX-red[1]. NrdI is a FDX which is involved in ribonucleotide reduction. WrbA (Tryptophan Repressor-Binding Protein) is also FDX. In E. coli there are 2 distinct flavodoxins: FDX I and II.

  • .
  • . Water molecules shown as red spheres.

3D Structures of Flavodoxin

Flavodoxin 3D structures


Apo-Flavodoxin from Helicobacter pylori complexed with benzamidine and chloride ion (PDB code 2bmv)

Drag the structure with the mouse to rotate

3D Structures of Flavodoxin3D Structures of Flavodoxin

Updated on 03-July-2019

ReferencesReferences

  1. Hoover DM, Ludwig ML. A flavodoxin that is required for enzyme activation: the structure of oxidized flavodoxin from Escherichia coli at 1.8 A resolution. Protein Sci. 1997 Dec;6(12):2525-37. PMID:9416602 doi:10.1002/pro.5560061205

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Jaime Prilusky