4bd6: Difference between revisions

<table><tr><td colspan='2'>[[4bd6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BD6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BD6 FirstGlance]. <br>

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bd2|4bd2]], [[4bd7|4bd7]], [[4bd8|4bd8]], [[4bdu|4bdu]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bd6 OCA], [http://pdbe.org/4bd6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bd6 RCSB], [http://www.ebi.ac.uk/pdbsum/4bd6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bd6 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/BAX_HUMAN BAX_HUMAN]] Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.<ref>PMID:8358790</ref> <ref>PMID:10772918</ref> <ref>PMID:8521816</ref> <ref>PMID:16113678</ref> <ref>PMID:18948948</ref> <ref>PMID:21199865</ref>   

*[[B-cell lymphoma protein|B-cell lymphoma protein]]