6jd0: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
==Structure of mutant human cathepsin L, engineered for GAG binding== | |||
<StructureSection load='6jd0' size='340' side='right'caption='[[6jd0]], [[Resolution|resolution]] 1.81Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6jd0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JD0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JD0 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=POL:N-PROPANOL'>POL</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_L Cathepsin L], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.15 3.4.22.15] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jd0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jd0 OCA], [http://pdbe.org/6jd0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jd0 RCSB], [http://www.ebi.ac.uk/pdbsum/6jd0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jd0 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN]] Important for the overall degradation of proteins in lysosomes. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Cathepsin L]] | |||
[[Category: Large Structures]] | |||
[[Category: Biswas, S]] | [[Category: Biswas, S]] | ||
[[Category: Choudhury, D]] | [[Category: Choudhury, D]] | ||
[[Category: Cathepsin l]] | |||
[[Category: Collagenase]] | |||
[[Category: Gag]] | |||
[[Category: Hydrolase]] |