4axm: Difference between revisions
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<StructureSection load='4axm' size='340' side='right'caption='[[4axm]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='4axm' size='340' side='right'caption='[[4axm]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4axm]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4axm]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AXM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AXM FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=V65:4-[(4-CHLOROBENZYL)(CYCLOHEXYL)AMINO]-6-MORPHOLIN-4-YL-1,3,5-TRIAZINE-2-CARBOXAMIDE'>V65</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=V65:4-[(4-CHLOROBENZYL)(CYCLOHEXYL)AMINO]-6-MORPHOLIN-4-YL-1,3,5-TRIAZINE-2-CARBOXAMIDE'>V65</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1cjl|1cjl]], [[1cs8|1cs8]], [[1icf|1icf]], [[1mhw|1mhw]], [[2vhs|2vhs]], [[2xu1|2xu1]], [[2xu3|2xu3]], [[2xu4|2xu4]], [[2xu5|2xu5]], [[2yj2|2yj2]], [[2yj8|2yj8]], [[2yj9|2yj9]], [[2yjb|2yjb]], [[2yjc|2yjc]], [[4axl|4axl]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1cjl|1cjl]], [[1cs8|1cs8]], [[1icf|1icf]], [[1mhw|1mhw]], [[2vhs|2vhs]], [[2xu1|2xu1]], [[2xu3|2xu3]], [[2xu4|2xu4]], [[2xu5|2xu5]], [[2yj2|2yj2]], [[2yj8|2yj8]], [[2yj9|2yj9]], [[2yjb|2yjb]], [[2yjc|2yjc]], [[4axl|4axl]]</div></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Cathepsin_L Cathepsin L], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.15 3.4.22.15] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4axm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4axm OCA], [https://pdbe.org/4axm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4axm RCSB], [https://www.ebi.ac.uk/pdbsum/4axm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4axm ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN]] Important for the overall degradation of proteins in lysosomes. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Cathepsin|Cathepsin]] | *[[Cathepsin 3D structures|Cathepsin 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Cathepsin L]] | [[Category: Cathepsin L]] | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Large Structures]] | |||
[[Category: Banner, D W]] | [[Category: Banner, D W]] | ||
[[Category: Benz, J]] | [[Category: Benz, J]] | ||