6akf: Difference between revisions

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==Crystal structure of mouse claudin-3 P134A mutant in complex with C-terminal fragment of Clostridium perfringens enterotoxin==
==Crystal structure of mouse claudin-3 P134A mutant in complex with C-terminal fragment of Clostridium perfringens enterotoxin==
<StructureSection load='6akf' size='340' side='right' caption='[[6akf]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
<StructureSection load='6akf' size='340' side='right'caption='[[6akf]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6akf]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_perfringens"_veillon_and_zuber_1898 "bacillus perfringens" veillon and zuber 1898] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AKF FirstGlance]. <br>
<table><tr><td colspan='2'>[[6akf]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AKF FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6ake|6ake]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cldn3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice]), cpe ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 "Bacillus perfringens" Veillon and Zuber 1898])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6akf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6akf OCA], [https://pdbe.org/6akf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6akf RCSB], [https://www.ebi.ac.uk/pdbsum/6akf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6akf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6akf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6akf OCA], [http://pdbe.org/6akf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6akf RCSB], [http://www.ebi.ac.uk/pdbsum/6akf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6akf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CLD3_MOUSE CLD3_MOUSE]] Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.<ref>PMID:10508613</ref> [[http://www.uniprot.org/uniprot/ELTB_CLOPF ELTB_CLOPF]] This enterotoxin is responsible for many cases of a mild type of food poisoning.
[https://www.uniprot.org/uniprot/CLD3_MOUSE CLD3_MOUSE] Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.<ref>PMID:10508613</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus perfringens veillon and zuber 1898]]
[[Category: Clostridium perfringens]]
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Fujiyoshi, Y]]
[[Category: Mus musculus]]
[[Category: Irie, K]]
[[Category: Fujiyoshi Y]]
[[Category: Nakamura, S]]
[[Category: Irie K]]
[[Category: Cell adhesion]]
[[Category: Nakamura S]]
[[Category: Membrane protein-toxin complex]]
[[Category: Tight junction]]

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