Sandbox Reserved 1502: Difference between revisions

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	An integrase is an enzyme required for the integration of viral DNA into the host genome. The process of integration can be divided into two sequential reactions. In the first one, named 3'-processing, the enzyme removes di- or trinucleotides from viral DNA ends to expose 3′-hydroxyls attached to CA dinucleotides. The second step is the insertion of the processed 3′-viral DNA ends into the host chromosomal DNA by a trans-esterification reaction. This is called the strand transfer.		An integrase is an enzyme required for the integration of viral DNA into the host genome. The process of integration can be divided into two sequential reactions. In the first one, named 3'-processing, the enzyme removes di- or trinucleotides from viral DNA ends to expose 3′-hydroxyls attached to CA dinucleotides. The second step is the insertion of the processed 3′-viral DNA ends into the host chromosomal DNA by a trans-esterification reaction. This is called the strand transfer.
	The HIV integrase is the enzyme responsible for the integration of the HIV's viral DNA into the host cell.~~[[Image:Ehxample.jpg]]~~		The HIV integrase is the enzyme responsible for the integration of the HIV's viral DNA into the host cell.