Sandbox Reserved 1489: Difference between revisions
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Experiments have shown that sodium increases the affinity of benzyl-hydantoin for Mhp1 and reciprocally benzyl-hydantoin increases the affinity of sodium for Mhp1. | Experiments have shown that sodium increases the affinity of benzyl-hydantoin for Mhp1 and reciprocally benzyl-hydantoin increases the affinity of sodium for Mhp1. | ||
Indeed, the presence of benzyl-hydantoin in Mhp1 binding site blocks the pathway of the sodium ion to the extracellular side.<ref>PMID 20413494</ref> | Indeed, the presence of benzyl-hydantoin in Mhp1 binding site blocks the pathway of the sodium ion to the extracellular side.<ref>PMID 20413494</ref> | ||
Therefore, the binding of the substrate and the cation are closely coupled. | Therefore, the binding of the substrate and the cation are closely coupled. | ||