4cpv: Difference between revisions

Revision as of 22:22, 4 May 2008

REFINED CRYSTAL STRUCTURE OF CALCIUM-LIGANDED CARP PARVALBUMIN 4.25 AT 1.5-ANGSTROMS RESOLUTION

OverviewOverview

The crystal structure of carp parvalbumin (pI = 4.25) has been refined by restrained least-squares analysis employing X-ray diffractometer data to 1.5-A resolution. The final residual for 12,653 reflections between 10 and 1.5 A with I(hkl) greater than 2 sigma(I) is 0.215. A total of 74 solvent molecules were included in the least-squares analysis. The root mean square deviation from ideality of bond lengths is 0.024 A. The model has a root mean square difference of 0.59 A from the positions of the main-chain atoms in a previously reported structure [Moews, P. C., & Kretsinger, R. H. (1975) J. Mol. Biol. 91, 201-228], which was refined by difference Fourier syntheses using data collected by film to 1.9 A. Although the overall features of the two models are very similar, there are significant differences in the amino-terminal region, which was extensively refit, and in the number of oxygen atoms liganding calcium in the CD and EF sites, which increased from six to seven in the CD site and decreased from eight to seven in the EF site.

About this StructureAbout this Structure

4CPV is a Single protein structure of sequence from Cyprinus carpio. Full crystallographic information is available from OCA.

ReferenceReference

Refined crystal structure of calcium-liganded carp parvalbumin 4.25 at 1.5-A resolution., Kumar VD, Lee L, Edwards BF, Biochemistry. 1990 Feb 13;29(6):1404-12. PMID:2334704 Page seeded by OCA on Sun May 4 22:22:36 2008

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OCA

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 [[Image:4cpv.gif|left|200px]]
- {{Structure
+<!--
-|PDB= 4cpv |SIZE=350|CAPTION= <scene name='initialview01'>4cpv</scene>, resolution 1.5&Aring;
+The line below this paragraph, containing "STRUCTURE_4cpv", creates the "Structure Box" on the page.
-|SITE=
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
-|LIGAND= <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-|ACTIVITY=
+or leave the SCENE parameter empty for the default display.
-|GENE=
+-->
-|DOMAIN=
+{{STRUCTURE_4cpv|  PDB=4cpv  |  SCENE=  }}
-|RELATEDENTRY=
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cpv OCA], [http://www.ebi.ac.uk/pdbsum/4cpv PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=4cpv RCSB]</span>
-}}
 '''REFINED CRYSTAL STRUCTURE OF CALCIUM-LIGANDED CARP PARVALBUMIN 4.25 AT 1.5-ANGSTROMS RESOLUTION'''
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 [[Category: Kumar, V D.]]
 [[Category: Lee, L.]]
-[[Category: calcium binding]]
+[[Category: Calcium binding]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 22:22:36 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:38:21 2008''