3cro: Difference between revisions

Revision as of 21:58, 4 May 2008

THE PHAGE 434 CRO/OR1 COMPLEX AT 2.5 ANGSTROMS RESOLUTION

OverviewOverview

The crystal structure of phage 434 Cro protein in complex with a 20 base-pair DNA fragment has been determined to 2.5 A resolution. The DNA fragment contains the sequence of the OR1 operator site. The structure shows a bent conformation for the DNA, straighter at the center and more bent at the ends. The central base-pairs adopt conformations with significant deviations from coplanarity. The two molecules interact extensively along their common interface, both through hydrogen bonds and van der Waals interactions. The significance of these interactions for operator binding and recognition is discussed.

About this StructureAbout this Structure

3CRO is a Single protein structure of sequence from Phage 434. Full crystallographic information is available from OCA.

ReferenceReference

The phage 434 Cro/OR1 complex at 2.5 A resolution., Mondragon A, Harrison SC, J Mol Biol. 1991 May 20;219(2):321-34. PMID:2038059 Page seeded by OCA on Sun May 4 21:58:16 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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 [[Image:3cro.jpg|left|200px]]
- {{Structure
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-}}
 '''THE PHAGE 434 CRO/OR1 COMPLEX AT 2.5 ANGSTROMS RESOLUTION'''
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 [[Category: Harrison, S C.]]
 [[Category: Mondragon, A.]]
-[[Category: double helix]]
+[[Category: Double helix]]
-[[Category: protein-dna complex]]
+[[Category: Protein-dna complex]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 21:58:16 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:32:43 2008''