6q5b: Difference between revisions

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-'''Unreleased structure'''
-The entry 6q5b is ON HOLD  until Paper Publication
+==OXA-48_P68A-AVI. Evolutionary trade-offs of OXA-48 mediated ceftazidime-avibactam resistance==
+<StructureSection load='6q5b' size='340' side='right'caption='[[6q5b]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
-Authors: Frohlich, C., Sorum, V., Thomassen, A.M., Johnsen, P.J., Leiros, H.K.S., Samuelsen, O.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6q5b]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Q5B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Q5B FirstGlance]. <br>
-Description: OXA-48_P68A-AVI. Evolutionary trade-offs of OXA-48 mediated ceftazidime-avibactam resistance
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO2:CARBON+DIOXIDE'>CO2</scene>, <scene name='pdbligand=NXL:(2S,5R)-1-FORMYL-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'>NXL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
-[[Category: Leiros, H.K.S]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6q5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6q5b OCA], [http://pdbe.org/6q5b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6q5b RCSB], [http://www.ebi.ac.uk/pdbsum/6q5b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6q5b ProSAT]</span></td></tr>
+</table>
+__TOC__
+</StructureSection>
+[[Category: Beta-lactamase]]
+[[Category: Large Structures]]
+[[Category: Frohlich, C]]
+[[Category: Johnsen, P J]]
+[[Category: Leiros, H K.S]]
 [[Category: Samuelsen, O]]
-[[Category: Frohlich, C]]
 [[Category: Sorum, V]]
-[[Category: Johnsen, P.J]]
+[[Category: Thomassen, A M]]
-[[Category: Thomassen, A.M]]
+[[Category: Antibiotic]]
+[[Category: Avibactam]]
+[[Category: Carbapenem]]
+[[Category: Carbapenemase]]
+[[Category: Ceftazidime]]
+[[Category: Escherichia coli]]
+[[Category: Evolution]]
+[[Category: Klebsiella pneumoniae]]
+[[Category: Oxa-48]]
+[[Category: Resistance development]]