6ivu: Difference between revisions

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-'''Unreleased structure'''
-The entry 6ivu is ON HOLD  until Paper Publication
+==Solution structure of the Sigma-anti-sigma factor complex RsgI1N-SigI1C from Clostridium thermocellum==
+<StructureSection load='6ivu' size='340' side='right'caption='[[6ivu]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
-Authors: Wei, Z., Feng, Y.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6ivu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cloth Cloth]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IVU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IVU FirstGlance]. <br>
-Description: Solution structure of the Sigma-anti-sigma factor complex RsgI1N-SigI1C from Clostridium thermocellum
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6ivs|6ivs]]</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cthe_0059 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=203119 CLOTH]), sigI1, Cthe_0058 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=203119 CLOTH])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ivu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ivu OCA], [http://pdbe.org/6ivu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ivu RCSB], [http://www.ebi.ac.uk/pdbsum/6ivu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ivu ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/RSGI1_CLOTH RSGI1_CLOTH]] Anti-sigma factor for SigI1. Negatively regulates SigI1 activity through direct interaction (PubMed:20937888). Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI1 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI1 (Probable).<ref>PMID:20937888</ref> <ref>PMID:20937888</ref>  [[http://www.uniprot.org/uniprot/SIGI1_CLOTH SIGI1_CLOTH]] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity). This sigma factor is involved in regulation of cellulosomal genes via an external polysaccharide-sensing mechanism. SigI1 promotes transcription from sigI1 and celS promoters (PubMed:20937888).[HAMAP-Rule:MF_02064]<ref>PMID:20937888</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Cloth]]
+[[Category: Large Structures]]
+[[Category: Feng, Y]]
 [[Category: Wei, Z]]
-[[Category: Feng, Y]]
+[[Category: Sigma factor]]
+[[Category: Transcription]]