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==Mouse Thymidylate Synthase Cocrystallized with N(4)OHdCMP and Soaked in Methylenetetrahydrofolate== | |||
<StructureSection load='6f6z' size='340' side='right' caption='[[6f6z]], [[Resolution|resolution]] 2.13Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6f6z]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F6Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F6Z FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NOH:2-DEOXY-N-HYDROXYCYTIDINE+5-(DIHYDROGEN+PHOSPHATE)'>NOH</scene>, <scene name='pdbligand=TGQ:(2~{S})-2-[[4-[[(6~{R})-2-azanyl-4-oxidanylidene-5,6,7,8-tetrahydro-1~{H}-pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic+acid'>TGQ</scene></td></tr> | |||
[[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr> | ||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f6z OCA], [http://pdbe.org/6f6z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f6z RCSB], [http://www.ebi.ac.uk/pdbsum/6f6z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f6z ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/TYSY_MOUSE TYSY_MOUSE]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Thymidylate synthase]] | |||
[[Category: Jarmula, A]] | [[Category: Jarmula, A]] | ||
[[Category: Maj, P]] | [[Category: Maj, P]] | ||
[[Category: Rode, W]] | |||
[[Category: Wilk, P]] | |||
[[Category: Cofactor]] | |||
[[Category: Enzyme]] | |||
[[Category: Inhibitor]] | |||
[[Category: Transferase]] | |||
Revision as of 11:17, 30 January 2019
Mouse Thymidylate Synthase Cocrystallized with N(4)OHdCMP and Soaked in MethylenetetrahydrofolateMouse Thymidylate Synthase Cocrystallized with N(4)OHdCMP and Soaked in Methylenetetrahydrofolate
Structural highlights
Function[TYSY_MOUSE] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity). |
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