3b2v: Difference between revisions

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[[Image:3b2v.jpg|left|200px]]
[[Image:3b2v.jpg|left|200px]]


{{Structure
<!--
|PDB= 3b2v |SIZE=350|CAPTION= <scene name='initialview01'>3b2v</scene>, resolution 3.30&Aring;
The line below this paragraph, containing "STRUCTURE_3b2v", creates the "Structure Box" on the page.
|SITE= <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+A+3281'>AC1</scene>, <scene name='pdbsite=AC2:Nag+Binding+Site+For+Residue+A+3282'>AC2</scene>, <scene name='pdbsite=AC3:Ndg+Binding+Site+For+Residue+A+3371'>AC3</scene>, <scene name='pdbsite=AC4:Nag+Binding+Site+For+Residue+A+3891'>AC4</scene>, <scene name='pdbsite=AC5:Nag+Binding+Site+For+Residue+A+4201'>AC5</scene> and <scene name='pdbsite=AC6:Nag+Binding+Site+For+Residue+A+5041'>AC6</scene>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span>
or leave the SCENE parameter empty for the default display.
|GENE= EGFR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), EGFR, ERBB1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
-->
|DOMAIN=
{{STRUCTURE_3b2v| PDB=3b2v  | SCENE= }}  
|RELATEDENTRY=[[3b2u|3B2U]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b2v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b2v OCA], [http://www.ebi.ac.uk/pdbsum/3b2v PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3b2v RCSB]</span>
}}


'''Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8'''
'''Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8'''
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[[Category: Kussie, P.]]
[[Category: Kussie, P.]]
[[Category: Li, S.]]
[[Category: Li, S.]]
[[Category: alternative splicing]]
[[Category: Alternative splicing]]
[[Category: anti-oncogene]]
[[Category: Anti-oncogene]]
[[Category: antigen:antibody complex]]
[[Category: Antigen:antibody complex]]
[[Category: antitumor]]
[[Category: Antitumor]]
[[Category: atp-binding]]
[[Category: Atp-binding]]
[[Category: cell cycle]]
[[Category: Cell cycle]]
[[Category: cell surface receptor]]
[[Category: Cell surface receptor]]
[[Category: disease mutation]]
[[Category: Disease mutation]]
[[Category: drug]]
[[Category: Drug]]
[[Category: fab fragment]]
[[Category: Fab fragment]]
[[Category: glycoprotein]]
[[Category: Glycoprotein]]
[[Category: immune system/transferase complex]]
[[Category: Immune system/transferase complex]]
[[Category: kinase]]
[[Category: Kinase]]
[[Category: membrane]]
[[Category: Membrane]]
[[Category: nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: polymorphism]]
[[Category: Polymorphism]]
[[Category: secreted]]
[[Category: Secreted]]
[[Category: transferase]]
[[Category: Transferase]]
[[Category: transmembrane]]
[[Category: Transmembrane]]
[[Category: tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
[[Category: ubl conjugation]]
[[Category: Ubl conjugation]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 20:20:16 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:22:31 2008''

Revision as of 20:20, 4 May 2008

File:3b2v.jpg

Template:STRUCTURE 3b2v

Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8


DiseaseDisease

Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]

About this StructureAbout this Structure

3B2V is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA. Page seeded by OCA on Sun May 4 20:20:16 2008

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