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| [[Image:2vgf.jpg|left|200px]] | | [[Image:2vgf.jpg|left|200px]] |
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| {{Structure
| | <!-- |
| |PDB= 2vgf |SIZE=350|CAPTION= <scene name='initialview01'>2vgf</scene>, resolution 2.75Å
| | The line below this paragraph, containing "STRUCTURE_2vgf", creates the "Structure Box" on the page. |
| |SITE= <scene name='pdbsite=AC1:Fbp+Binding+Site+For+Chain+A'>AC1</scene>, <scene name='pdbsite=AC2:Pga+Binding+Site+For+Chain+A'>AC2</scene>, <scene name='pdbsite=AC3:K+Binding+Site+For+Chain+A'>AC3</scene>, <scene name='pdbsite=AC4:Mn+Binding+Site+For+Chain+A'>AC4</scene>, <scene name='pdbsite=AC5:Fbp+Binding+Site+For+Chain+B'>AC5</scene>, <scene name='pdbsite=AC6:Pga+Binding+Site+For+Chain+B'>AC6</scene>, <scene name='pdbsite=AC7:K+Binding+Site+For+Chain+B'>AC7</scene>, <scene name='pdbsite=AC8:Mn+Binding+Site+For+Chain+B'>AC8</scene>, <scene name='pdbsite=AC9:Fbp+Binding+Site+For+Chain+C'>AC9</scene>, <scene name='pdbsite=BC1:Pga+Binding+Site+For+Chain+C'>BC1</scene>, <scene name='pdbsite=BC2:K+Binding+Site+For+Chain+C'>BC2</scene>, <scene name='pdbsite=BC3:Mn+Binding+Site+For+Chain+C'>BC3</scene>, <scene name='pdbsite=BC4:Fbp+Binding+Site+For+Chain+D'>BC4</scene>, <scene name='pdbsite=BC5:Pga+Binding+Site+For+Chain+D'>BC5</scene>, <scene name='pdbsite=BC6:K+Binding+Site+For+Chain+D'>BC6</scene> and <scene name='pdbsite=BC7:Mn+Binding+Site+For+Chain+D'>BC7</scene>
| | You may change the PDB parameter (which sets the PDB file loaded into the applet) |
| |LIGAND= <scene name='pdbligand=FBP:FRUCTOSE-1,6-DIPHOSPHATE'>FBP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PGA:2-PHOSPHOGLYCOLIC+ACID'>PGA</scene>
| | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), |
| |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span>
| | or leave the SCENE parameter empty for the default display. |
| |GENE= | | --> |
| |DOMAIN= | | {{STRUCTURE_2vgf| PDB=2vgf | SCENE= }} |
| |RELATEDENTRY=[[2vgb|2VGB]], [[2vgg|2VGG]]
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| |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vgf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vgf OCA], [http://www.ebi.ac.uk/pdbsum/2vgf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2vgf RCSB]</span>
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| }} | |
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| '''HUMAN ERYTHROCYTE PYRUVATE KINASE: T384M MUTANT''' | | '''HUMAN ERYTHROCYTE PYRUVATE KINASE: T384M MUTANT''' |
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| ==About this Structure== | | ==About this Structure== |
| 2VGF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 1LIW. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VGF OCA]. | | 2VGF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1liw 1liw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VGF OCA]. |
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| ==Reference== | | ==Reference== |
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| [[Category: Wang, C.]] | | [[Category: Wang, C.]] |
| [[Category: Zanella, A.]] | | [[Category: Zanella, A.]] |
| [[Category: alternative splicing]] | | [[Category: Alternative splicing]] |
| [[Category: disease mutation]] | | [[Category: Disease mutation]] |
| [[Category: glycolysis]] | | [[Category: Glycolysis]] |
| [[Category: kinase]] | | [[Category: Kinase]] |
| [[Category: magnesium]] | | [[Category: Magnesium]] |
| [[Category: metal-binding]] | | [[Category: Metal-binding]] |
| [[Category: phosphorylation]] | | [[Category: Phosphorylation]] |
| [[Category: polymorphism]] | | [[Category: Polymorphism]] |
| [[Category: pyruvate]] | | [[Category: Pyruvate]] |
| [[Category: pyruvate kinase in the active r-state]] | | [[Category: Pyruvate kinase in the active r-state]] |
| [[Category: transferase]] | | [[Category: Transferase]] |
| | | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 18:45:40 2008'' |
| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:11:55 2008'' | |