Transfer RNA (tRNA): Difference between revisions

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At the acceptor end, amino acid can be attached via the 3'-OH group. At the opposite end of the molecule is the anticodon, which pairs with its complementary codon on the messenger RNA.  
At the acceptor end, amino acid can be attached via the 3'-OH group. At the opposite end of the molecule is the anticodon, which pairs with its complementary codon on the messenger RNA.  
   
   
The two arms of the "L" are formed by the <scene name='43/433638/Stemstacking/1'>stacking of the acceptor and TΨC-stem</scene>Text  on one side, and of the anticodon and D-stem on the other side. <scene name='43/433638/Kissing/2'>Tertiary interactions between the TΨC- and D-loop</scene> form the corner of the L-shape and stabilise the structure. Non-Watson-Crick hydrogen bonding is important in this core.  
The two arms of the "L" are formed by the <scene name='43/433638/Stemstacking/1'>stacking of the acceptor and TΨC-stem</scene>Text  on one side, and of the anticodon and D-stem on the other side. <scene name='43/433638/Kissing/2'>Tertiary interactions between the TΨC- and D-loop</scene> form the corner of the L-shape and stabilise the structure. Non-Watson-Crick hydrogen bonding is important in this core (visualize interactively at [http://jmol.x3dna.org/ DSSR Jmol web interface)]).
In addition, tRNA have a variable loop located in between the acceptor and D-stems. This variable loop can be quite small, but for some tRNA such as the serine or leucine-specific tRNA, it can form an additional helix.  
In addition, tRNA have a variable loop located in between the acceptor and D-stems. This variable loop can be quite small, but for some tRNA such as the serine or leucine-specific tRNA, it can form an additional helix.  


Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Frédéric Dardel, Wayne Decatur, Michal Harel, Alexander Berchansky, Ann Taylor, Joel L. Sussman, Karsten Theis