2rk8: Difference between revisions

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[[Image:2rk8.jpg|left|200px]]
[[Image:2rk8.jpg|left|200px]]


{{Structure
<!--
|PDB= 2rk8 |SIZE=350|CAPTION= <scene name='initialview01'>2rk8</scene>, resolution 2.000&Aring;
The line below this paragraph, containing "STRUCTURE_2rk8", creates the "Structure Box" on the page.
|SITE= <scene name='pdbsite=AC1:Mn+Binding+Site+For+Residue+A+700'>AC1</scene>, <scene name='pdbsite=AC2:Na+Binding+Site+For+Residue+A+624'>AC2</scene>, <scene name='pdbsite=AC3:Mn+Binding+Site+For+Residue+B+700'>AC3</scene>, <scene name='pdbsite=AC4:Na+Binding+Site+For+Residue+B+624'>AC4</scene>, <scene name='pdbsite=AC5:Ppf+Binding+Site+For+Residue+A+3969'>AC5</scene>, <scene name='pdbsite=AC6:Ppf+Binding+Site+For+Residue+B+3969'>AC6</scene>, <scene name='pdbsite=AC7:Fmt+Binding+Site+For+Residue+A+3406'>AC7</scene>, <scene name='pdbsite=AC8:Peg+Binding+Site+For+Residue+A+5759'>AC8</scene> and <scene name='pdbsite=AC9:Fmt+Binding+Site+For+Residue+B+3406'>AC9</scene>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PPF:PHOSPHONOFORMIC+ACID'>PPF</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(GTP) Phosphoenolpyruvate carboxykinase (GTP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.32 4.1.1.32] </span>
or leave the SCENE parameter empty for the default display.
|GENE= Pck1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])
-->
|DOMAIN=
{{STRUCTURE_2rk8| PDB=2rk8  | SCENE= }}  
|RELATEDENTRY=[[2rk7|2RK7]], [[2rka|2RKA]], [[2rkd|2RKD]], [[2rke|2RKE]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rk8 OCA], [http://www.ebi.ac.uk/pdbsum/2rk8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2rk8 RCSB]</span>
}}


'''The Structure of rat cytosolic PEPCK in complex with phosphonoformate'''
'''The Structure of rat cytosolic PEPCK in complex with phosphonoformate'''
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==Reference==
==Reference==
Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition., Stiffin RM, Sullivan SM, Carlson GM, Holyoak T, Biochemistry. 2008 Feb 19;47(7):2099-109. Epub 2008 Jan 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18197707 18197707]
Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition., Stiffin RM, Sullivan SM, Carlson GM, Holyoak T, Biochemistry. 2008 Feb 19;47(7):2099-109. Epub 2008 Jan 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18197707 18197707]
[[Category: Phosphoenolpyruvate carboxykinase (GTP)]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: Stiffin, R M.]]
[[Category: Stiffin, R M.]]
[[Category: Sullivan, S M.]]
[[Category: Sullivan, S M.]]
[[Category: cytoplasm]]
[[Category: Cytoplasm]]
[[Category: decarboxylase]]
[[Category: Decarboxylase]]
[[Category: gluconeogenesis]]
[[Category: Gluconeogenesis]]
[[Category: gtp-binding]]
[[Category: Gtp-binding]]
[[Category: kinase]]
[[Category: Kinase]]
[[Category: lyase]]
[[Category: Lyase]]
[[Category: nucleotide-binding]]
[[Category: Nucleotide-binding]]
 
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