6mgp: Difference between revisions
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==Structure of human 4-1BB / 4-1BBL complex== | |||
<StructureSection load='6mgp' size='340' side='right' caption='[[6mgp]], [[Resolution|resolution]] 2.13Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6mgp]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MGP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MGP FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6mge|6mge]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mgp OCA], [http://pdbe.org/6mgp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mgp RCSB], [http://www.ebi.ac.uk/pdbsum/6mgp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mgp ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/TNFL9_HUMAN TNFL9_HUMAN]] Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. [[http://www.uniprot.org/uniprot/TNR9_HUMAN TNR9_HUMAN]] Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Chin, S M]] | |||
[[Category: Kimberlin, C R]] | |||
[[Category: Roe-Zurz, Z]] | |||
[[Category: Xu, A]] | |||
[[Category: Yang, Y]] | |||
[[Category: 4-1bb]] | |||
[[Category: 4-1bbl]] | |||
[[Category: Cd137]] | |||
[[Category: Cd137l]] | |||
[[Category: Complex]] | |||
[[Category: Immune system]] | |||
[[Category: Signaling]] | |||
[[Category: Tnfrsf]] | |||
[[Category: Tnfsf]] |