2rkq: Difference between revisions

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==Crystal structure of drosophila peptidoglycan recognition protein SD (PGRP-SD)==
==Crystal structure of drosophila peptidoglycan recognition protein SD (PGRP-SD)==
<StructureSection load='2rkq' size='340' side='right' caption='[[2rkq]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='2rkq' size='340' side='right'caption='[[2rkq]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2rkq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RKQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2rkq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RKQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RKQ FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PGRP-SD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PGRP-SD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rkq OCA], [http://pdbe.org/2rkq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rkq RCSB], [http://www.ebi.ac.uk/pdbsum/2rkq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2rkq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rkq OCA], [https://pdbe.org/2rkq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rkq RCSB], [https://www.ebi.ac.uk/pdbsum/2rkq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rkq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PGPSD_DROME PGPSD_DROME]] Peptidoglycan-recognition protein that plays a key role in innate immnunity by binding to peptidoglycans (PGN) of Gram-positive bacteria and activating the Toll pathway. Has no activity against on Gram-negative bacteria and fungi. Shows some partial redundancy with PRPGP-SA in Gram-positive bacteria recognition. May act by activating the proteolytic cleavage of Spatzle and the subsequent activation of Toll pathway. Recognizes S.aureus PGN.<ref>PMID:15448690</ref>   
[[https://www.uniprot.org/uniprot/PGPSD_DROME PGPSD_DROME]] Peptidoglycan-recognition protein that plays a key role in innate immnunity by binding to peptidoglycans (PGN) of Gram-positive bacteria and activating the Toll pathway. Has no activity against on Gram-negative bacteria and fungi. Shows some partial redundancy with PRPGP-SA in Gram-positive bacteria recognition. May act by activating the proteolytic cleavage of Spatzle and the subsequent activation of Toll pathway. Recognizes S.aureus PGN.<ref>PMID:15448690</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Drome]]
[[Category: Drome]]
[[Category: Large Structures]]
[[Category: Kellenberger, C]]
[[Category: Kellenberger, C]]
[[Category: Leone, P]]
[[Category: Leone, P]]

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