P53: Difference between revisions
No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='' size='350' side='right' scene='26/26327/P53-dna/2' caption='Human p53 DNA-binding domain complex with DNA and Zn+2 ion (magenta) (PDB Code [[1tup]])'> | <StructureSection load='' size='350' side='right' scene='26/26327/P53-dna/2' caption='Human p53 DNA-binding domain complex with DNA and Zn+2 ion (magenta) (PDB Code [[1tup]])'> | ||
__TOC__ | __TOC__ | ||
==p53 Tumor Suppressor Protein (PDB ID [[1tup]])== | ==p53 Tumor Suppressor Protein (PDB ID [[1tup]])== | ||
| Line 51: | Line 51: | ||
** [[2xwr]], [[2ocj]], [[2ybg]] – h-p53 DBD – human<BR /> | ** [[2xwr]], [[2ocj]], [[2ybg]] – h-p53 DBD – human<BR /> | ||
** [[2fej]] - h-p53 DBD - NMR<BR /> | ** [[2fej]] - h-p53 DBD - NMR<BR /> | ||
** [[2wgx]], [[3d05]], [[3d06]], [[3d07]], [[3d08]], [[3d09]], [[2pcx]], [[2j1w]], [[2j1x]], [[2j1y]], [[2j1z]], [[2j20]], [[2j21]], [[2bim]], [[2bin]], [[2bio]], [[2bip]], [[2biq]], [[1uol]], [[4kvp]], [[4lo9]], [[4loe]], [[4lof]], [[4ibq]], [[4ibs]], [[4ibt]], [[4iby]], [[4ibz]], [[4ijt]], [[4mzi]], [[5lap]] - h-p53 DBD (mutant) <BR /> | ** [[2wgx]], [[3d05]], [[3d06]], [[3d07]], [[3d08]], [[3d09]], [[2pcx]], [[2j1w]], [[2j1x]], [[2j1y]], [[2j1z]], [[2j20]], [[2j21]], [[2bim]], [[2bin]], [[2bio]], [[2bip]], [[2biq]], [[1uol]], [[4kvp]], [[4lo9]], [[4loe]], [[4lof]], [[4ibq]], [[4ibs]], [[4ibt]], [[4iby]], [[4ibz]], [[4ijt]], [[4mzi]], [[5lap]], [[6ff9]] - h-p53 DBD (mutant) <BR /> | ||
** [[2ioi]], [[2ioo]], [[1hu8]] – m-p53 DBD – mouse<BR /> | ** [[2ioi]], [[2ioo]], [[1hu8]] – m-p53 DBD – mouse<BR /> | ||
** [[1t4w]] – p53-like DBD – ''Caenoharbditis elegans'' | ** [[1t4w]] – p53-like DBD – ''Caenoharbditis elegans'' | ||
| Line 57: | Line 57: | ||
* p53 DNA-binding domain complex with DNA | * p53 DNA-binding domain complex with DNA | ||
** [[3igk]], [[3igl]], [[3kz8]], [[3kmd]], [[2ac0]], [[2ady]], [[2ahi]], [[2ata]], [[1tsr]], [[1tup]], [[4hje]], [[5bua]] – h-p53 DBD + DNA<BR /> | ** [[3igk]], [[3igl]], [[3kz8]], [[3kmd]], [[2ac0]], [[2ady]], [[2ahi]], [[2ata]], [[1tsr]], [[1tup]], [[4hje]], [[5bua]], [[6fj5]], [[5mg7]], [[5mf7]], [[5mcw]], [[5mcu]], [[5mct]], [[5lgy]] – h-p53 DBD + DNA<BR /> | ||
** [[3d0a]], [[3ts8]], [[4ibu]], [[4ibv]], [[4ibw]] - h-p53 DBD (mutant) + DNA<BR /> | ** [[3d0a]], [[3ts8]], [[4ibu]], [[4ibv]], [[4ibw]] - h-p53 DBD (mutant) + DNA<BR /> | ||
** [[3q05]], [[3q06]] - h-p53 DBD + TD + DNA<br /> | ** [[3q05]], [[3q06]] - h-p53 DBD + TD + DNA<br /> | ||
| Line 68: | Line 68: | ||
**[[5aoi]], [[5ab9]] - h-p53 DBD (mutant) + indole derivative<br /> | **[[5aoi]], [[5ab9]] - h-p53 DBD (mutant) + indole derivative<br /> | ||
** [[2vuk]] - h-p53 DBD + drug<BR /> | ** [[2vuk]] - h-p53 DBD + drug<BR /> | ||
**[[5g4o]], [[5g4n]], [[5g4m]], [[5aom]], [[5aok]], [[5aba]], [[5a7b]] - h-p53 DBD (mutant) + drug<br /> | **[[5g4o]], [[5g4n]], [[5g4m]], [[5aom]], [[5aok]], [[5aba]], [[5a7b]], [[5o1i]], [[5o1h]], [[5o1g]], [[5o1f]], [[5o1e]], [[5o1a]], [[5o1b]], [[5o1c]], [[5o1d]] - h-p53 DBD (mutant) + drug<br /> | ||
** [[2iom]] - m-p53 DBD + propanol | ** [[2iom]] - m-p53 DBD + propanol | ||