5my0: Difference between revisions

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==KS-MAT DI-DOMAIN OF MOUSE FAS WITH MALONYL-COA==
==KS-MAT DI-DOMAIN OF MOUSE FAS WITH MALONYL-COA==
<StructureSection load='5my0' size='340' side='right' caption='[[5my0]], [[Resolution|resolution]] 2.94&Aring;' scene=''>
<StructureSection load='5my0' size='340' side='right'caption='[[5my0]], [[Resolution|resolution]] 2.94&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5my0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MY0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MY0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5my0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MY0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MY0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MLC:MALONYL-COENZYME+A'>MLC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.94&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=K5L:'>K5L</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=K5L:(2~{R})-2-azanyl-3-(3-oxidanyl-3-oxidanylidene-propanoyl)oxy-propanoic+acid'>K5L</scene>, <scene name='pdbligand=MLC:MALONYL-COENZYME+A'>MLC</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Fasn ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5my0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5my0 OCA], [https://pdbe.org/5my0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5my0 RCSB], [https://www.ebi.ac.uk/pdbsum/5my0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5my0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5my0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5my0 OCA], [http://pdbe.org/5my0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5my0 RCSB], [http://www.ebi.ac.uk/pdbsum/5my0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5my0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FAS_MOUSE FAS_MOUSE]] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.  
[https://www.uniprot.org/uniprot/FAS_MOUSE FAS_MOUSE] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Fatty acid synthase|Fatty acid synthase]]
*[[Fatty acid synthase 3D structures|Fatty acid synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Grininger, M]]
[[Category: Mus musculus]]
[[Category: Huu, K V]]
[[Category: Grininger M]]
[[Category: Paithankar, K S]]
[[Category: Huu KV]]
[[Category: Rittner, A]]
[[Category: Paithankar KS]]
[[Category: Mouse fatty-acid-synthase ks-mat malonyl-coa]]
[[Category: Rittner A]]
[[Category: Transferase]]

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