6gz2: Difference between revisions
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==Crystal Structure of the LeuO Effector Binding Domain== | |||
<StructureSection load='6gz2' size='340' side='right'caption='[[6gz2]], [[Resolution|resolution]] 1.94Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6gz2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GZ2 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6gz0|6gz0]], [[6gz1|6gz1]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gz2 OCA], [http://pdbe.org/6gz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gz2 RCSB], [http://www.ebi.ac.uk/pdbsum/6gz2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gz2 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/LEUO_ECOLI LEUO_ECOLI]] A global transcription factor. Activates transcription of the 9 following operons; yjjQ-bglJ, yjjP, acrEF, ybdO, yjcRQP, casABCDE12, rhsD-ybbC, fepE and gltF, in most cases it probably interferes with silencing by H-NS and activates transcription. Represses transcription of the 3 following operons; uxaCA, sdaCB and btsT. H-NS repression of the bgl operon, leading to the ability to metabolize some beta-glucosides. It also directly activates the bgl operon. Activation is H-NS and BglJ-RcsB independent.<ref>PMID:19429622</ref> <ref>PMID:20659289</ref> <ref>PMID:20952573</ref> <ref>PMID:9422614</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Baumann, U]] | |||
[[Category: Fragel, S]] | [[Category: Fragel, S]] | ||
[[Category: Montada, A | [[Category: Montada, A M]] | ||
[[Category: Schacherl, M]] | [[Category: Schacherl, M]] | ||
[[Category: Schnetz, K]] | [[Category: Schnetz, K]] | ||
[[Category: Lttr]] | |||
[[Category: Transcription]] | |||
[[Category: Transcription factor]] |