6e8f: Difference between revisions
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The entry | ==Crystal Structure of Human Protocadherin-15 EC3-5 CD2-1== | ||
<StructureSection load='6e8f' size='340' side='right'caption='[[6e8f]], [[Resolution|resolution]] 2.99Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6e8f]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E8F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E8F FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e8f OCA], [http://pdbe.org/6e8f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e8f RCSB], [http://www.ebi.ac.uk/pdbsum/6e8f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e8f ProSAT]</span></td></tr> | ||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/PCD15_HUMAN PCD15_HUMAN]] Usher syndrome type 1;Autosomal recessive non-syndromic sensorineural deafness type DFNB. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting distinct genetic loci, including the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PCD15_HUMAN PCD15_HUMAN]] Calcium-dependent cell-adhesion protein. Essential for maintenance of normal retinal and cochlear function. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Choudhary, D]] | |||
[[Category: Sotomayor, M]] | |||
[[Category: Tamilselvan, E]] | |||
[[Category: Calcium-binding protein]] | |||
[[Category: Cell adhesion]] | |||
[[Category: Hair cell]] | |||
[[Category: Mechanotransduction]] | |||
[[Category: Stereocilia]] | |||
[[Category: Tip link]] | |||
Revision as of 09:12, 31 July 2019
Crystal Structure of Human Protocadherin-15 EC3-5 CD2-1Crystal Structure of Human Protocadherin-15 EC3-5 CD2-1
Structural highlights
Disease[PCD15_HUMAN] Usher syndrome type 1;Autosomal recessive non-syndromic sensorineural deafness type DFNB. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting distinct genetic loci, including the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. Function[PCD15_HUMAN] Calcium-dependent cell-adhesion protein. Essential for maintenance of normal retinal and cochlear function. |
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