2nui: Difference between revisions
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'''X-ray Structure of synthetic [D83A]RNase A''' | '''X-ray Structure of synthetic [D83A]RNase A''' | ||
==Overview== | |||
The total chemical synthesis of RNase A using modern chemical ligation methods is described, illustrating the significant advances that have been made in chemical protein synthesis since Gutte and Merrifield's pioneering preparation of RNase A in 1969. The identity of the synthetic product was confirmed through rigorous characterization, including the determination of the X-ray crystal structure to 1.1 Angstrom resolution. (c) 2007 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 90:278-286, 2008.This article was originally published online as an accepted preprint. The "Published Online" date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com. | |||
==About this Structure== | ==About this Structure== | ||
2NUI is a [[Single protein]] structure | 2NUI is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NUI OCA]. | ||
==Reference== | ==Reference== | ||
Total synthesis by modern chemical ligation methods | Total synthesis by modern chemical ligation methods and high resolution (1.1 A) X-ray structure of ribonuclease A., Boerema DJ, Tereshko VA, Kent SB, Biopolymers. 2008;90(3):278-86. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17610259 17610259] | ||
[[Category: Pancreatic ribonuclease]] | [[Category: Pancreatic ribonuclease]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: Kent, S B.H.]] | [[Category: Kent, S B.H.]] | ||
[[Category: Tereshko, V A.]] | [[Category: Tereshko, V A.]] | ||
[[Category: | [[Category: Hydrolase]] | ||
[[Category: | [[Category: Synthetic protein]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 09:55:37 2008'' | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | |||
Revision as of 09:55, 4 May 2008
X-ray Structure of synthetic [D83A]RNase A
OverviewOverview
The total chemical synthesis of RNase A using modern chemical ligation methods is described, illustrating the significant advances that have been made in chemical protein synthesis since Gutte and Merrifield's pioneering preparation of RNase A in 1969. The identity of the synthetic product was confirmed through rigorous characterization, including the determination of the X-ray crystal structure to 1.1 Angstrom resolution. (c) 2007 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 90:278-286, 2008.This article was originally published online as an accepted preprint. The "Published Online" date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com.
About this StructureAbout this Structure
2NUI is a Single protein structure. Full crystallographic information is available from OCA.
ReferenceReference
Total synthesis by modern chemical ligation methods and high resolution (1.1 A) X-ray structure of ribonuclease A., Boerema DJ, Tereshko VA, Kent SB, Biopolymers. 2008;90(3):278-86. PMID:17610259 Page seeded by OCA on Sun May 4 09:55:37 2008