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==Ruthenium Hexammine ion interactions with Z-DNA== | ==Ruthenium Hexammine ion interactions with Z-DNA== | ||
<StructureSection load='2htt' size='340' side='right' caption='[[2htt]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='2htt' size='340' side='right'caption='[[2htt]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2htt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HTT FirstGlance]. <br> | <table><tr><td colspan='2'>[[2htt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HTT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HTT FirstGlance]. <br> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Bharanidharan, D]] | [[Category: Bharanidharan, D]] | ||
[[Category: Gautham, N]] | [[Category: Gautham, N]] | ||
Revision as of 13:15, 1 April 2020
Ruthenium Hexammine ion interactions with Z-DNARuthenium Hexammine ion interactions with Z-DNA
Structural highlights
Publication Abstract from PubMedThe hexamer duplex d(CGCGCA).d(TGCGCG) was crystallized with hexammineruthenium(III) ions in an orthorhombic space group; the crystals diffracted to 1.54 A resolution. Strong ion interactions with the adenine base induce a tautomeric shift from the amino to the imino form. Consequently, the A.T base pairing is disrupted. This structural study may be relevant to metal toxicity. Hexammineruthenium(III) ion interactions with Z-DNA.,Bharanidharan D, Thiyagarajan S, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt, 12):1008-13. Epub 2007 Nov 21. PMID:18084080[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See AlsoReferences
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