6fdf: Difference between revisions
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==Crystal structure of S. pombe Dnmt2 methyltransferase== | ==Crystal structure of S. pombe Dnmt2 methyltransferase== | ||
<StructureSection load='6fdf' size='340' side='right' caption='[[6fdf]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='6fdf' size='340' side='right'caption='[[6fdf]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6fdf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FDF OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[6fdf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FDF FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.697Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fdf OCA], [https://pdbe.org/6fdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fdf RCSB], [https://www.ebi.ac.uk/pdbsum/6fdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fdf ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PMT1M_SCHPO PMT1M_SCHPO] Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp). Can also methylate cytosine 38 in tRNA(Glu), albeit to a lower level, but not tRNA(Lys). Pmt1-dependent tRNA methylation is induced by nitrogen limitation and depends on the nutrient-sensing protein kinase sck2. Does not have DNA-methylation activity.<ref>PMID:23074192</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 6fdf" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6fdf" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Schizosaccharomyces pombe]] | ||
[[Category: | [[Category: Ficner R]] | ||
[[Category: Johannsson S]] | |||
[[Category: Neumann P]] | |||
[[Category: S | |||
[[Category: | |||