GTPase KRas: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
The GDP-bound KRas binds a <scene name='78/781207/Cv/2'>small molecule inhibitor in its binding cleft</scene> following conformational change of the protein<ref>PMID:22566140</ref>. | The GDP-bound KRas binds a <scene name='78/781207/Cv/2'>small molecule inhibitor in its binding cleft</scene> following conformational change of the protein<ref>PMID:22566140</ref>. Water molecules are shown as red spheres. | ||
*<scene name='78/781207/Cv/9'>Inhibitor binding cleft</scene>. | *<scene name='78/781207/Cv/9'>Inhibitor binding cleft</scene>. | ||
*<scene name='78/781207/Cv/7'>GDP binding site</scene>. | *<scene name='78/781207/Cv/7'>GDP binding site</scene>. | ||