User:Luis Netto/Sandbox 1: Difference between revisions

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Ohr (Organic Hydroperoxide Resistance Protein)[[1zb8]] is a Cys based peroxidase <ref>PMID: 12540833</ref>,<ref>PMID: 12485986</ref>
Ohr (Organic Hydroperoxide Resistance Protein)[[1zb8]] is a Cys based peroxidase <ref>PMID: 12540833</ref>,<ref>PMID: 12485986</ref>


that display higher preference for hydrogen peroxide than for organic hydroperoxides.  
that display higher preference for hydrogen peroxide (H2O2) than for organic hydroperoxides. Accordingly, bacteria with the gene for Ohr deleted displayed increased sensitivity for organic hydroperoxides but not for hydrogen peroxide.
 
 
 
 
 
 
 
 
Ohr is a tight homo-dimer a  [[Image:Ohr_black_white.png | thumb]]
 


It is involved in the response of


Ohr is a dimer glu arg in the active site [[Image:Ohr_black_white.png | thumb]]
glu arg in the active site




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== Function ==
== Function ==
Ohr is a Cys based peroxidase that means the active site Cys is very reactive towards organic hydroperoxides. This high reactivity is achieved in the active site by interactions with fully conserved Arg and Glu residues among others==Your Heading Here (maybe something like 'Structure')==
<StructureSection load='1ZB8' size='350' side='right' caption='Escherichia coli reca protein-bound DNA (PDB entry [[3rec]])' scene=''>
Anything in this section will appear adjacent to the 3D structure and will be scrollable.
</StructureSection>
It is involved in the response of


== Disease ==
== Disease ==