5xyz: Difference between revisions

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==The structure of human BTK kinase domain in complex with a covalent inhibitor==
==The structure of human BTK kinase domain in complex with a covalent inhibitor==
<StructureSection load='5xyz' size='340' side='right' caption='[[5xyz]], [[Resolution|resolution]] 2.64&Aring;' scene=''>
<StructureSection load='5xyz' size='340' side='right'caption='[[5xyz]], [[Resolution|resolution]] 2.64&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5xyz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XYZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XYZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[5xyz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XYZ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5XYZ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GYL:N-[3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-1H-1,2,4-triazol-3-yl)phenyl]propanamide'>GYL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GYL:N-[3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-1H-1,2,4-triazol-3-yl)phenyl]propanamide'>GYL</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xyz OCA], [http://pdbe.org/5xyz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xyz RCSB], [http://www.ebi.ac.uk/pdbsum/5xyz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xyz ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5xyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xyz OCA], [http://pdbe.org/5xyz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xyz RCSB], [http://www.ebi.ac.uk/pdbsum/5xyz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xyz ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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</div>
</div>
<div class="pdbe-citations 5xyz" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5xyz" style="background-color:#fffaf0;"></div>
==See Also==
*[[Tyrosine kinase 3D structures|Tyrosine kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Cao, R]]
[[Category: Cao, R]]

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