6cod: Difference between revisions

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'''Unreleased structure'''


The entry 6cod is ON HOLD until Paper Publication
==AtHNL enantioselectivity mutant At-A9-H7 Apo Y13C,Y121L,P126F,L128W,C131T,F179L,A209I with benzaldehyde==
 
<StructureSection load='6cod' size='340' side='right'caption='[[6cod]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6cod]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6COD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6COD FirstGlance]. <br>
Description:  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HBX:BENZALDEHYDE'>HBX</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(R)-mandelonitrile_lyase (R)-mandelonitrile lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.10 4.1.2.10] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cod OCA], [http://pdbe.org/6cod PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cod RCSB], [http://www.ebi.ac.uk/pdbsum/6cod PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cod ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/HNL_ARATH HNL_ARATH]] Involved in cyanogenesis, the release of HCN from injured tissues (By similarity). Displays R-selective hydroxynitrile lyase activity. Also accepts nitromethane (MeNO2) as a donor in a reaction with aromatic aldehydes to yield (R)-beta-nitro alcohols.<ref>PMID:18467465</ref> <ref>PMID:19433222</ref> <ref>PMID:21439333</ref> <ref>PMID:17907254</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Desrouleaux, R]]
[[Category: Jones, B J]]
[[Category: Kazlauskas, R J]]
[[Category: Alpha beta hydrolase globular hydroxynitrile lyase]]
[[Category: Lyase]]

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