Estrogen receptor: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 11: | Line 11: | ||
==Estrogen receptor α complexed with raloxifene and a corepressor peptide== | ==Estrogen receptor α complexed with raloxifene and a corepressor peptide== | ||
<scene name='Estrogen_receptor/Cv/1'>Click here to see the difference between conformations</scene> of estrogen receptor α complexed with raloxifene and a corepressor peptide (morph was taken from [http://molmovdb.org/cgi-bin/movie.cgi Gallery of Morphs] of the [http://molmovdb.org Yale Morph Server]). | <scene name='Estrogen_receptor/Cv/1'>Click here to see the difference between conformations</scene> of estrogen receptor α complexed with raloxifene and a corepressor peptide (morph was taken from [http://molmovdb.org/cgi-bin/movie.cgi Gallery of Morphs] of the [http://molmovdb.org Yale Morph Server]). | ||
==3D structures of estrogen receptor== | |||
[[Estrogen receptor 3D structures]] | |||
</StructureSection> | </StructureSection> | ||
| Line 29: | Line 33: | ||
*Estrogen receptor α ligand binding domain residues 245-554 | *Estrogen receptor α ligand binding domain residues 245-554 | ||
**[[1a52]], [[1g50]] - hERα LBD - human<br /> | **[[1a52]], [[1g50]] - hERα LBD - human<br /> | ||
**[[1ere]], [[1qku]] - hERα LBD + EST<BR /> | **[[1ere]], [[1qku]] - hERα LBD + EST<BR /> | ||
| Line 38: | Line 41: | ||
**[[2bj4]], [[2jf9]], [[2jfa]], [[1pcg]], [[5gtr]], [[5gs4]] - hERα LBD + peptide antagonist<br /> | **[[2bj4]], [[2jf9]], [[2jfa]], [[1pcg]], [[5gtr]], [[5gs4]] - hERα LBD + peptide antagonist<br /> | ||
**[[2q6j]], [[2p15]], [[3erd]], [[1l2i]] - hERα LBD + GRIP peptide<br /> | **[[2q6j]], [[2p15]], [[3erd]], [[1l2i]] - hERα LBD + GRIP peptide<br /> | ||
**[[6cbz]] - hERα LBD (mutant) + GRIP peptide + estradiol<br /> | **[[6d0f]], [[6czn]] - hERα LBD (mutant) + GRIP peptide<br /> | ||
**[[6cbz]], [[5wgq]], [[5wgd]] - hERα LBD (mutant) + GRIP peptide + estradiol<br /> | |||
**[[4q13]] - hERα LBD (mutant) + glucocorticoid receptor-interacting protein peptide<br /> | **[[4q13]] - hERα LBD (mutant) + glucocorticoid receptor-interacting protein peptide<br /> | ||
**[[5krf]] - hERα LBD (mutant) + peptide + anti-hormone<br /> | **[[5krf]] - hERα LBD (mutant) + peptide + anti-hormone<br /> | ||
**[[2yat]] - hERα LBD (mutant) + EST derivative<br /> | **[[2yat]] - hERα LBD (mutant) + EST derivative<br /> | ||
**[[6iar]], [[6dfn]], [[6df6]] - hERα LBD + antagonist<br /> | |||
**[[5fqp]], [[5fqr]], [[5fqs]], [[5fqt]], [[5fqv]], [[5aau]], [[5aav]], [[5acc]], [[5ak2]], [[5di7]], [[5did]], [[5die]], [[5dig]], [[5dk9]], [[5dkb]], [[5dke]], [[5dkg]], [[5dks]], [[5dl4]], [[5dlr]], [[5dmc]], [[5dmf]], [[5dp0]], [[6chz]], [[6chw]], [[6c42]], [[6b0f]], [[5w9d]], [[5ufx]], [[5ufw]] - hERα LBD (mutant) + antagonist<br /> | **[[5fqp]], [[5fqr]], [[5fqs]], [[5fqt]], [[5fqv]], [[5aau]], [[5aav]], [[5acc]], [[5ak2]], [[5di7]], [[5did]], [[5die]], [[5dig]], [[5dk9]], [[5dkb]], [[5dke]], [[5dkg]], [[5dks]], [[5dl4]], [[5dlr]], [[5dmc]], [[5dmf]], [[5dp0]], [[6chz]], [[6chw]], [[6c42]], [[6b0f]], [[5w9d]], [[5ufx]], [[5ufw]] - hERα LBD (mutant) + antagonist<br /> | ||
**[[4q50]] - hERα LBD (mutant) + tamoxifen derivative<br /> | **[[6owc]] - hERα LBD (mutant) + pyridine derivative<br /> | ||
**[[4q50]], [[5w9c]] - hERα LBD (mutant) + tamoxifen derivative<br /> | |||
**[[3uuc]] - hERα LBD + bisphenol<br /> | **[[3uuc]] - hERα LBD + bisphenol<br /> | ||
**[[5t1z]] - hERα LBD + LXXLL motif (mutant) + ethoxy triphenylethylene<br /> | **[[5t1z]] - hERα LBD + LXXLL motif (mutant) + ethoxy triphenylethylene<br /> | ||
| Line 50: | Line 56: | ||
**[[2yja]] - hERα LBD + NCAO2 peptide<br /> | **[[2yja]] - hERα LBD + NCAO2 peptide<br /> | ||
**[[2b23]] - hERα LBD (mutant) + NCAO2 peptide<br /> | **[[2b23]] - hERα LBD (mutant) + NCAO2 peptide<br /> | ||
**[[4n1y]] - ERα LBD – pacific oyster<br /> | |||
*''ERα LBD ternary complex with nuclear receptor coactivator 2 peptide (NCAO2)'' | *''ERα LBD ternary complex with nuclear receptor coactivator 2 peptide (NCAO2)'' | ||