2arj: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
==CD8alpha-alpha in complex with YTS 105.18 Fab== | ==CD8alpha-alpha in complex with YTS 105.18 Fab== | ||
<StructureSection load='2arj' size='340' side='right' caption='[[2arj]], [[Resolution|resolution]] 2.88Å' scene=''> | <StructureSection load='2arj' size='340' side='right'caption='[[2arj]], [[Resolution|resolution]] 2.88Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2arj]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2arj]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ARJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ARJ FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nez|1nez]], [[1bqh|1bqh]], [[1akj|1akj]], [[1cd8|1cd8]], [[1q69|1q69]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1nez|1nez]], [[1bqh|1bqh]], [[1akj|1akj]], [[1cd8|1cd8]], [[1q69|1q69]]</div></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd8a, Lyt-2, Lyt2 ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd8a, Lyt-2, Lyt2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2arj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2arj OCA], [https://pdbe.org/2arj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2arj RCSB], [https://www.ebi.ac.uk/pdbsum/2arj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2arj ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/CD8A_MOUSE CD8A_MOUSE]] Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Line 31: | Line 31: | ||
==See Also== | ==See Also== | ||
*[[CD8|CD8]] | *[[CD8 3D structures|CD8 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] |