User:Andrea Foote/Sandbox 1: Difference between revisions
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== Interactions == | == Interactions == | ||
Purα is known to interact with: | Purα is known to interact with: | ||
*Purβ | |||
*Serum response factor (SRF) | |||
*Y-box-binding protein 1 (YB-1) (MSY1 in mice) | |||
*Retinoblastoma protein (RB) | |||
*Rm62 RNA helicase of HIV | |||
== Disease == | == Disease == | ||
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Fragile X-associated Tremor/Ataxia Syndrome (FXTAS) is another disease associated with abnormal activity of Purα. Normally between __ and __ copies of __ , however in greater than __ copies can result in ___ causing delayed-onset neurological problems. FXTAS generally develops in middle age, and is characterized by tremor, ataxia, and ___. | Fragile X-associated Tremor/Ataxia Syndrome (FXTAS) is another disease associated with abnormal activity of Purα. Normally between __ and __ copies of __ , however in greater than __ copies can result in ___ causing delayed-onset neurological problems. FXTAS generally develops in middle age, and is characterized by tremor, ataxia, and ___. | ||
== Additional Resources == | |||
For more information on PURA syndrome, visit the PURA Syndrome Foundation website: [https://www.purasyndrome.org] | |||
JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> | JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> | ||