1zw3: Difference between revisions

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==Vinculin Head (0-258) in Complex with the Talin Rod residues 1630-1652==
==Vinculin Head (0-258) in Complex with the Talin Rod residues 1630-1652==
<StructureSection load='1zw3' size='340' side='right' caption='[[1zw3]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
<StructureSection load='1zw3' size='340' side='right'caption='[[1zw3]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1zw3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZW3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZW3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1zw3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZW3 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zvz|1zvz]], [[1zw2|1zw2]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1zvz|1zvz]], [[1zw2|1zw2]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VCL, VINC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VCL, VINC1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zw3 OCA], [http://pdbe.org/1zw3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zw3 RCSB], [http://www.ebi.ac.uk/pdbsum/1zw3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zw3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zw3 OCA], [https://pdbe.org/1zw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zw3 RCSB], [https://www.ebi.ac.uk/pdbsum/1zw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zw3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK]] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref>  [[http://www.uniprot.org/uniprot/TLN1_MOUSE TLN1_MOUSE]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.  
[[https://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK]] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref>  [[https://www.uniprot.org/uniprot/TLN1_MOUSE TLN1_MOUSE]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1zw3" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1zw3" style="background-color:#fffaf0;"></div>
==See Also==
*[[Talin|Talin]]
*[[Vinculin|Vinculin]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Chick]]
[[Category: Chick]]
[[Category: Large Structures]]
[[Category: Barsukov, I L]]
[[Category: Barsukov, I L]]
[[Category: Critchley, D R]]
[[Category: Critchley, D R]]

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