1zw3: Difference between revisions
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==Vinculin Head (0-258) in Complex with the Talin Rod residues 1630-1652== | ==Vinculin Head (0-258) in Complex with the Talin Rod residues 1630-1652== | ||
<StructureSection load='1zw3' size='340' side='right' caption='[[1zw3]], [[Resolution|resolution]] 3.30Å' scene=''> | <StructureSection load='1zw3' size='340' side='right'caption='[[1zw3]], [[Resolution|resolution]] 3.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1zw3]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1zw3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZW3 FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zvz|1zvz]], [[1zw2|1zw2]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1zvz|1zvz]], [[1zw2|1zw2]]</div></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VCL, VINC1 ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VCL, VINC1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zw3 OCA], [https://pdbe.org/1zw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zw3 RCSB], [https://www.ebi.ac.uk/pdbsum/1zw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zw3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK]] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref> [[https://www.uniprot.org/uniprot/TLN1_MOUSE TLN1_MOUSE]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</div> | </div> | ||
<div class="pdbe-citations 1zw3" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 1zw3" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Talin|Talin]] | |||
*[[Vinculin|Vinculin]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Chick]] | [[Category: Chick]] | ||
[[Category: Large Structures]] | |||
[[Category: Barsukov, I L]] | [[Category: Barsukov, I L]] | ||
[[Category: Critchley, D R]] | [[Category: Critchley, D R]] |