Complement C5: Difference between revisions

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 == Function ==
-'''Complement C5''' (CC5) is the fifth component of the complement system.  The complement system is part of the innate immune system.  CC5 is composed of α chain (C5a) and β chain (C5b).  Proteoplytic degradation of CC5 produces <scene name='70/705685/Cv/2'>anaphylatoxin</scene> which is a mediator of local inflammatory process.  The C terminal domain of CC5 (residues 1530-1676) is homologous to a domain in netrins and is named <scene name='70/705685/Cv/3'>C345C</scene>.  Activation of CC5 by C5 convertase initiates the assembly of the C5 to C9 components into the membrane attack complex. <ref>PMID:18536718</ref>
+'''Complement C5''' (CC5) is the fifth component of the complement system.  The complement system is part of the innate immune system.  CC5 is composed of α chain (C5a) and β chain (C5b).  Proteoplytic degradation of CC5 produces <scene name='70/705685/Cv/4'>anaphylatoxin</scene> which is a mediator of local inflammatory process.  The C terminal domain of CC5 (residues 1530-1676) is homologous to a domain in netrins and is named <scene name='70/705685/Cv/5'>C345C</scene>.  Activation of CC5 by C5 convertase initiates the assembly of the C5 to C9 components into the membrane attack complex. <ref>PMID:18536718</ref>
 == Disease ==