1uf8: Difference between revisions

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==Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-Phenylalanine==
==Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-Phenylalanine==
<StructureSection load='1uf8' size='340' side='right' caption='[[1uf8]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='1uf8' size='340' side='right'caption='[[1uf8]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1uf8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Agrsp Agrsp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UF8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UF8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1uf8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Agrsp Agrsp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UF8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UF8 FirstGlance]. <br>
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</StructureSection>
</StructureSection>
[[Category: Agrsp]]
[[Category: Agrsp]]
[[Category: Large Structures]]
[[Category: N-carbamoyl-D-amino-acid hydrolase]]
[[Category: N-carbamoyl-D-amino-acid hydrolase]]
[[Category: Aoki, M]]
[[Category: Aoki, M]]

Revision as of 16:08, 1 January 2020

Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-PhenylalanineCrystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-Phenylalanine

Structural highlights

1uf8 is a 2 chain structure with sequence from Agrsp. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:N-carbamoyl-D-amino-acid hydrolase, with EC number 3.5.1.77
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[DCAS_AGRSK] The enzyme catalyzes the hydrolysis of N-carbamoyl-D-amino acids to the corresponding which are useful intermediates in the preparation of beta-lactam antibiotics. Industrial production of beta-lactam antibiotics is now being developed using this enzyme.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1uf8, resolution 1.80Å

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