1ujy: Difference between revisions
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==Solution structure of SH3 domain in Rac/Cdc42 guanine nucleotide exchange factor(GEF) 6== | ==Solution structure of SH3 domain in Rac/Cdc42 guanine nucleotide exchange factor(GEF) 6== | ||
<StructureSection load='1ujy' size='340' side='right' caption='[[1ujy]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='1ujy' size='340' side='right'caption='[[1ujy]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ujy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UJY OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[1ujy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UJY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1UJY FirstGlance]. <br> | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KAZUSA ha01154 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KAZUSA ha01154 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1ujy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ujy OCA], [http://pdbe.org/1ujy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ujy RCSB], [http://www.ebi.ac.uk/pdbsum/1ujy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ujy ProSAT], [http://www.topsan.org/Proteins/RSGI/1ujy TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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==See Also== | ==See Also== | ||
*[[Rho guanine nucleotide exchange factor|Rho guanine nucleotide exchange factor]] | *[[Rho guanine nucleotide exchange factor 3D structures|Rho guanine nucleotide exchange factor 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Large Structures]] | |||
[[Category: Aoki, M]] | [[Category: Aoki, M]] | ||
[[Category: He, F]] | [[Category: He, F]] | ||
Revision as of 10:28, 30 December 2020
Solution structure of SH3 domain in Rac/Cdc42 guanine nucleotide exchange factor(GEF) 6Solution structure of SH3 domain in Rac/Cdc42 guanine nucleotide exchange factor(GEF) 6
Structural highlights
Disease[ARHG6_HUMAN] Defects in ARHGEF6 are the cause of mental retardation X-linked type 46 (MRX46) [MIM:300436]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.[1] Function[ARHG6_HUMAN] Acts as a RAC1 guanine nucleotide exchange factor (GEF). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences
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