1twr: Difference between revisions

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==Crystal structures of ferrous and ferrous-NO forms of verdoheme in a complex with human heme oxygenase-1: catalytic implications for heme cleavage==
==Crystal structures of ferrous and ferrous-NO forms of verdoheme in a complex with human heme oxygenase-1: catalytic implications for heme cleavage==
<StructureSection load='1twr' size='340' side='right' caption='[[1twr]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='1twr' size='340' side='right'caption='[[1twr]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1twr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TWR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TWR FirstGlance]. <br>
<table><tr><td colspan='2'>[[1twr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TWR OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1TWR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NO:NITRIC+OXIDE'>NO</scene>, <scene name='pdbligand=VER:IRON-OCTAETHYLPORPHYRIN'>VER</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO:NITRIC+OXIDE'>NO</scene>, <scene name='pdbligand=VER:IRON-OCTAETHYLPORPHYRIN'>VER</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1twn|1twn]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1twn|1twn]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HMOX1, HO1, HO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HMOX1, HO1, HO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Heme_oxygenase Heme oxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.3 1.14.99.3] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Heme_oxygenase Heme oxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.3 1.14.99.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1twr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1twr OCA], [http://pdbe.org/1twr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1twr RCSB], [http://www.ebi.ac.uk/pdbsum/1twr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1twr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1twr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1twr OCA], [http://pdbe.org/1twr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1twr RCSB], [http://www.ebi.ac.uk/pdbsum/1twr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1twr ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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==See Also==
==See Also==
*[[Heme oxygenase|Heme oxygenase]]
*[[Heme oxygenase 3D structures|Heme oxygenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Heme oxygenase]]
[[Category: Heme oxygenase]]
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Lad, L]]
[[Category: Lad, L]]
[[Category: Montellano, P R.Ortiz de]]
[[Category: Montellano, P R.Ortiz de]]

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