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==Crystal structure of Plasmodium falciparum topoisomerase II DNA-binding, cleavage and re-ligation domain== | |||
<StructureSection load='6ca8' size='340' side='right' caption='[[6ca8]], [[Resolution|resolution]] 2.33Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6ca8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CA8 FirstGlance]. <br> | |||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TopoII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ca8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ca8 OCA], [http://pdbe.org/6ca8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ca8 RCSB], [http://www.ebi.ac.uk/pdbsum/6ca8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ca8 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/Q7Z2D0_PLAFA Q7Z2D0_PLAFA]] Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.[RuleBase:RU362094] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Plafa]] | |||
[[Category: Kandavelu, P]] | |||
[[Category: Kumar, S]] | [[Category: Kumar, S]] | ||
[[Category: | [[Category: Rathod, P K]] | ||
[[Category: Dna-binding domain]] | |||
[[Category: Isomerase]] | |||
[[Category: Topoisomerase]] | |||
Revision as of 11:15, 21 February 2019
Crystal structure of Plasmodium falciparum topoisomerase II DNA-binding, cleavage and re-ligation domainCrystal structure of Plasmodium falciparum topoisomerase II DNA-binding, cleavage and re-ligation domain
Structural highlights
Function[Q7Z2D0_PLAFA] Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.[RuleBase:RU362094] |
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