Nuclear receptor corepressor: Difference between revisions

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== Function ==
== Function ==


'''Nuclear receptor corepressors''' (N-CoR)  and '''SMRT''' (Silencing Mediator of Retinoic acid and Thyroid hormone receptor) mediate the repression of gene subscription by nuclear receptors<ref>PMID:11845213</ref>.  NCORs contain interaction domains containing a conserved LXXII hydrophobic motif.  This motif resembles the LXXLL motif of nuclear receptors<ref>PMID:11117528</ref>.
'''Nuclear receptor corepressors''' (N-CoR)  and '''SMRT''' (Silencing Mediator of Retinoic acid and Thyroid hormone receptor) mediate the repression of gene subscription by nuclear receptors<ref>PMID:11845213</ref>.  N-CoRs contain interaction domains with a conserved LXXII hydrophobic motif.  This motif resembles the LXXLL motif of nuclear receptors<ref>PMID:11117528</ref>.


== Relevance ==
== Relevance ==

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman