Nuclear receptor corepressor: Difference between revisions
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== Function == | == Function == | ||
'''Nuclear receptor corepressors''' (N-CoR) and '''SMRT''' (Silencing Mediator of Retinoic acid and Thyroid hormone receptor) mediate the repression of gene subscription by nuclear receptors<ref>PMID:11845213</ref>. | '''Nuclear receptor corepressors''' (N-CoR) and '''SMRT''' (Silencing Mediator of Retinoic acid and Thyroid hormone receptor) mediate the repression of gene subscription by nuclear receptors<ref>PMID:11845213</ref>. N-CoRs contain interaction domains with a conserved LXXII hydrophobic motif. This motif resembles the LXXLL motif of nuclear receptors<ref>PMID:11117528</ref>. | ||
== Relevance == | == Relevance == |