VprBP: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
The interactions between VprBP and Vpr are located in a cleft formed by <scene name='77/776391/Cv/5'>VprBD canonical WD40 seven-blade β-propeller</scene> ({{Template:ColorKey_Helix}}, {{Template:ColorKey_Strand}}, {{Template:ColorKey_Loop}}, {{Template:ColorKey_Turn}}) which is <scene name='77/776391/Cv/6'>lined by acidic residues on one end and hydrophobic residues at the center</scene> ({{Template:ColorKey_Charge_Anionic}} / {{Template:ColorKey_Charge_Cationic}}; {{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}}). The interactions are formed by <scene name='77/776391/Cv/7'>hydrogen bonds</scene>, <scene name='77/776391/Cv/8'>Vpr Phe residue buried in VprBP hydrophobic pocket</scene> and VprBP Trp binding to residues in Vpr pocket<ref>PMID:27571178</ref>. | The interactions between VprBP and Vpr are located in a cleft formed by <scene name='77/776391/Cv/5'>VprBD canonical WD40 seven-blade β-propeller</scene> ({{Template:ColorKey_Helix}}, {{Template:ColorKey_Strand}}, {{Template:ColorKey_Loop}}, {{Template:ColorKey_Turn}}) which is <scene name='77/776391/Cv/6'>lined by acidic residues on one end and hydrophobic residues at the center</scene> ({{Template:ColorKey_Charge_Anionic}} / {{Template:ColorKey_Charge_Cationic}}; {{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}}). The interactions are formed by <scene name='77/776391/Cv/7'>hydrogen bonds</scene>, <scene name='77/776391/Cv/8'>Vpr Phe residue buried in VprBP hydrophobic pocket</scene> and <scene name='77/776391/Cv/9'>VprBP Trp binding to residues in Vpr pocket</scene><ref>PMID:27571178</ref>. | ||
</StructureSection> | </StructureSection> | ||
== 3D Structures of VprBP == | == 3D Structures of VprBP == | ||