5mxj: Difference between revisions

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==Structure of the Y108F mutant of vanillyl alcohol oxidase==
==Structure of the Y108F mutant of vanillyl alcohol oxidase==
<StructureSection load='5mxj' size='340' side='right' caption='[[5mxj]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='5mxj' size='340' side='right'caption='[[5mxj]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5mxj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_10495 Atcc 10495]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MXJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MXJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[5mxj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Penicillium_simplicissimum Penicillium simplicissimum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MXJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VAOA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=69488 ATCC 10495])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Vanillyl-alcohol_oxidase Vanillyl-alcohol oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.38 1.1.3.38] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mxj OCA], [https://pdbe.org/5mxj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mxj RCSB], [https://www.ebi.ac.uk/pdbsum/5mxj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mxj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mxj OCA], [http://pdbe.org/5mxj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mxj RCSB], [http://www.ebi.ac.uk/pdbsum/5mxj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mxj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/VAOX_PENSI VAOX_PENSI]] Catalyzes the conversion of vanillin alcohol to vanillin, and also the conversion of a wide range of phenolic compounds bearing side chains of variable size at the para position of the aromatic ring. Crucial for the degradation of the secondary metabolites derived from the degradation of the lignin. Catalyzes besides the oxidation of 4-hydroxybenzyl alcohols, the oxidative deamination of 4-hydroxybenzylamines, the oxidative demethylation of 4-(methoxy-methyl)phenols and the oxidative hydration of 4-allylphenols. Most active with 4-allylphenols.  
[https://www.uniprot.org/uniprot/VAOX_PENSI VAOX_PENSI] Catalyzes the conversion of vanillin alcohol to vanillin, and also the conversion of a wide range of phenolic compounds bearing side chains of variable size at the para position of the aromatic ring. Crucial for the degradation of the secondary metabolites derived from the degradation of the lignin. Catalyzes besides the oxidation of 4-hydroxybenzyl alcohols, the oxidative deamination of 4-hydroxybenzylamines, the oxidative demethylation of 4-(methoxy-methyl)phenols and the oxidative hydration of 4-allylphenols. Most active with 4-allylphenols.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5mxj" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5mxj" style="background-color:#fffaf0;"></div>
==See Also==
*[[Vanillyl-alcohol oxidase|Vanillyl-alcohol oxidase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 10495]]
[[Category: Large Structures]]
[[Category: Vanillyl-alcohol oxidase]]
[[Category: Penicillium simplicissimum]]
[[Category: Allan, R C]]
[[Category: Allan RC]]
[[Category: Berkel, W J.H van]]
[[Category: Binda C]]
[[Category: Binda, C]]
[[Category: Ewing TA]]
[[Category: Ewing, T A]]
[[Category: Fraaije MW]]
[[Category: Fraaije, M W]]
[[Category: Gygli G]]
[[Category: Gygli, G]]
[[Category: Mattevi A]]
[[Category: Mattevi, A]]
[[Category: Nguyen Q-T]]
[[Category: Nguyen, Q T]]
[[Category: Romero E]]
[[Category: Romero, E]]
[[Category: Van Berkel WJH]]
[[Category: Oxidoreductase]]
[[Category: Vanillyl alcohol oxidase]]
[[Category: Y108f mutant]]

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