6f6j: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of the Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO1 with Fe(II)/succinate/(3S)-3-hydroxy-L-lysine== | |||
<StructureSection load='6f6j' size='340' side='right' caption='[[6f6j]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6f6j]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F6J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F6J FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CUW:(2~{S},3~{R})-2,6-bis(azanyl)-3-oxidanyl-hexanoic+acid'>CUW</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f6j OCA], [http://pdbe.org/6f6j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f6j RCSB], [http://www.ebi.ac.uk/pdbsum/6f6j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f6j ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/LYS3O_CATAD LYS3O_CATAD]] Alpha-ketoglutarate-dependent dioxygenase that in vitro catalyzes the regio- and stereoselective hydroxylation of L-lysine, leading to (3S)-3-hydroxy-L-lysine. Can also use (5R)-5-hydroxy-L-lysine as substrate, but neither D-lysine nor L-ornithine.[REFERENCE:2] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bastard, K]] | |||
[[Category: Isabet, T]] | |||
[[Category: Legrand, P]] | [[Category: Legrand, P]] | ||
[[Category: | [[Category: Stura, E A]] | ||
[[Category: Zaparucha, A]] | [[Category: Zaparucha, A]] | ||
[[Category: | [[Category: Dioxygenase]] | ||
[[Category: Enzyme]] | |||
[[Category: Feii alphakg form]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Oxydoreductase]] | |||
Revision as of 11:18, 14 November 2018
Crystal structure of the Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO1 with Fe(II)/succinate/(3S)-3-hydroxy-L-lysineCrystal structure of the Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO1 with Fe(II)/succinate/(3S)-3-hydroxy-L-lysine
Structural highlights
Function[LYS3O_CATAD] Alpha-ketoglutarate-dependent dioxygenase that in vitro catalyzes the regio- and stereoselective hydroxylation of L-lysine, leading to (3S)-3-hydroxy-L-lysine. Can also use (5R)-5-hydroxy-L-lysine as substrate, but neither D-lysine nor L-ornithine.[REFERENCE:2] |
| ||||||||||||||||