6c2g: Difference between revisions

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-'''Unreleased structure'''
-The entry 6c2g is ON HOLD
+==Human triosephosphate isomerase mutant V231M==
+<StructureSection load='6c2g' size='340' side='right' caption='[[6c2g]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-Authors: Torres, L.A., Enriquez, F.S.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6c2g]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6C2G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6C2G FirstGlance]. <br>
-Description: Human triosephosphate isomerase mutant V231M
+</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6c2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6c2g OCA], [http://pdbe.org/6c2g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6c2g RCSB], [http://www.ebi.ac.uk/pdbsum/6c2g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6c2g ProSAT]</span></td></tr>
-[[Category: Torres, L.A]]
+</table>
-[[Category: Enriquez, F.S]]
+== Disease ==
+[[http://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN]] Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:[http://omim.org/entry/190450 190450]]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.
+__TOC__
+</StructureSection>
+[[Category: Triose-phosphate isomerase]]
+[[Category: Enriquez, F S]]
+[[Category: Torres, L A]]
+[[Category: Isomerase]]