6bst: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bst OCA], [http://pdbe.org/6bst PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bst RCSB], [http://www.ebi.ac.uk/pdbsum/6bst PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bst ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bst OCA], [http://pdbe.org/6bst PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bst RCSB], [http://www.ebi.ac.uk/pdbsum/6bst PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bst ProSAT]</span></td></tr> | ||
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== Publication Abstract from PubMed == | |||
DNA oligomer duplexes with alternating cytosines and guanines in their sequence tend to form helices of the Z-DNA type, where the sugar and phosphate backbone forms a left-handed helix in a zigzag fashion with a repeat of two successive Watson-Crick pairs of nucleotides. Z-DNA duplexes often crystallize in complexes with diverse metal ions interacting with polar DNA atoms in various ways. This work describes the high-resolution crystal structure of a Z-DNA d(CGCGCG)2 duplex in complex with Ca(2+) ions, unusually coordinated as an approximate pentagonal bipyramid by two neighboring guanines through their O6 and N7 atoms and a water molecule in the equatorial plane and a phosphate oxygen atom and another water molecule in the apical positions. | |||
The crystal structure of Z-DNA with untypically coordinated Ca(2+) ions.,Luo Z, Dauter Z J Biol Inorg Chem. 2017 Dec 21. pii: 10.1007/s00775-017-1526-4. doi:, 10.1007/s00775-017-1526-4. PMID:29270817<ref>PMID:29270817</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
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<div class="pdbe-citations 6bst" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Z-DNA|Z-DNA]] | |||
== References == | |||
<references/> | |||
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</StructureSection> | </StructureSection> | ||
Revision as of 11:43, 10 January 2018
CRYSTAL STRUCTURE OF Z-DNA WITH UNTYPICALLY COORDINATED CA2+ IONCRYSTAL STRUCTURE OF Z-DNA WITH UNTYPICALLY COORDINATED CA2+ ION
Structural highlights
Publication Abstract from PubMedDNA oligomer duplexes with alternating cytosines and guanines in their sequence tend to form helices of the Z-DNA type, where the sugar and phosphate backbone forms a left-handed helix in a zigzag fashion with a repeat of two successive Watson-Crick pairs of nucleotides. Z-DNA duplexes often crystallize in complexes with diverse metal ions interacting with polar DNA atoms in various ways. This work describes the high-resolution crystal structure of a Z-DNA d(CGCGCG)2 duplex in complex with Ca(2+) ions, unusually coordinated as an approximate pentagonal bipyramid by two neighboring guanines through their O6 and N7 atoms and a water molecule in the equatorial plane and a phosphate oxygen atom and another water molecule in the apical positions. The crystal structure of Z-DNA with untypically coordinated Ca(2+) ions.,Luo Z, Dauter Z J Biol Inorg Chem. 2017 Dec 21. pii: 10.1007/s00775-017-1526-4. doi:, 10.1007/s00775-017-1526-4. PMID:29270817[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See AlsoReferences
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