6b4t: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
No edit summary
No edit summary
Line 1: Line 1:
'''Unreleased structure'''


The entry 6b4t is ON HOLD  until Paper Publication
==Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 4-methylpyridin-2-ol==
 
<StructureSection load='6b4t' size='340' side='right' caption='[[6b4t]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
Authors: Faheem, M., Neto, J.B., Collins, P., Pearce, N.M., Valadares, N.F., Bird, L., Pereira, H.M., Delft, F.V., Barbosa, J.A.R.G.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6b4t]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B4T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6B4T FirstGlance]. <br>
Description: Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 4-methylpyridin-2-ol
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CQJ:4-methylpyridin-2-ol'>CQJ</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
[[Category: Pearce, N.M]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cxq|5cxq]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6b4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b4t OCA], [http://pdbe.org/6b4t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6b4t RCSB], [http://www.ebi.ac.uk/pdbsum/6b4t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6b4t ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/A0A0U3AGT1_SCHMA A0A0U3AGT1_SCHMA]] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477]
__TOC__
</StructureSection>
[[Category: Purine-nucleoside phosphorylase]]
[[Category: Barbosa, J A.R G]]
[[Category: Bird, L]]
[[Category: Collins, P]]
[[Category: Collins, P]]
[[Category: Pereira, H.M]]
[[Category: Delft, F V]]
[[Category: Barbosa, J.A.R.G]]
[[Category: Bird, L]]
[[Category: Faheem, M]]
[[Category: Faheem, M]]
[[Category: Delft, F.V]]
[[Category: Neto, J B]]
[[Category: Neto, J.B]]
[[Category: Pearce, N M]]
[[Category: Valadares, N.F]]
[[Category: Pereira, H M]]
[[Category: Valadares, N F]]
[[Category: Purine nucleoside phosphorylase]]
[[Category: Transferase]]
[[Category: Transferase-inhibitor complex]]

Revision as of 10:44, 3 October 2018

Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 4-methylpyridin-2-olCrystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 4-methylpyridin-2-ol

Structural highlights

6b4t is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
NonStd Res:
Activity:Purine-nucleoside phosphorylase, with EC number 2.4.2.1
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[A0A0U3AGT1_SCHMA] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477]

6b4t, resolution 1.51Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA