Calreticulin: Difference between revisions
Michal Harel (talk | contribs) New page: <StructureSection load='6eny' size='340' side='right' caption='Human calreticulin (gold) complex with β-microglobulin (green), tapasin (pink), protein disulfide-isomerase (yellow) MHC c... |
No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='6eny' size='340' side='right' caption='Human calreticulin (gold) complex with β-microglobulin (green), tapasin (pink), protein disulfide-isomerase (yellow) MHC class I antigen (cyan) (PDB code [[6eny]]) ' scene=''> | <StructureSection load='6eny' size='340' side='right' caption='Human calreticulin (gold) complex with β-microglobulin (green), tapasin (pink), protein disulfide-isomerase (yellow) MHC class I antigen (cyan) (PDB code [[6eny]]) ' scene=''> | ||
| Line 17: | Line 16: | ||
== Structural highlights == | == Structural highlights == | ||
CALR structure consists of 3 domains: N-terminal globular domain which has chaperone function; P-domain which is proline-rich, binds Ca+2 with high affinity and possesses a lectin-like chaperone function; C-terminal domain containing an ER retention signal. | <scene name='77/776393/Cv/1'>CALR structure consists of 3 domains</scene>: N-terminal globular domain which has chaperone function; P-domain which is proline-rich, binds Ca+2 with high affinity and possesses a lectin-like chaperone function; C-terminal domain containing an ER retention signal. | ||
</StructureSection> | </StructureSection> | ||