Unusual sequence numbering: Difference between revisions
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The numbering of protein and nucleic acid sequences is arbitrary in structure files from the [[PDB|World Wide Protein Data Bank]] (PDB). | The numbering of protein and nucleic acid sequences is arbitrary in structure files from the [[PDB|World Wide Protein Data Bank]] (PDB). That is, authors are free to number sequences as they wish. | ||
'''Straightforward numbering''' assigns 1 to the amino-terminal amino acid, and counts up sequentially and monotonically to the carboxy-terminal amino acid. An example is [http://firstglance.jmol.org/fgij/fg.htm?1pgb 1pgb] ([[1pgb]]). The crystallized protein is numbered 1-56, despite it being a fragment of a [http://www.uniprot.org/uniprot/P06654#sequences 448-residue full length sequence] that begins (after adding an N-terminal Met) at full-length sequence number 228. | '''Straightforward numbering''' assigns 1 to the amino-terminal amino acid, and counts up sequentially and monotonically to the carboxy-terminal amino acid. An example is [http://firstglance.jmol.org/fgij/fg.htm?1pgb 1pgb] ([[1pgb]]). The crystallized protein is numbered 1-56, despite it being a fragment of a [http://www.uniprot.org/uniprot/P06654#sequences 448-residue full length sequence] that begins (after adding an N-terminal Met) at full-length sequence number 228. | ||