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==Crystal structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription== | |||
<StructureSection load='6bog' size='340' side='right' caption='[[6bog]], [[Resolution|resolution]] 3.21Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6bog]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3dmq 3dmq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BOG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BOG FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[ | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bog FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bog OCA], [http://pdbe.org/6bog PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bog RCSB], [http://www.ebi.ac.uk/pdbsum/6bog PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bog ProSAT]</span></td></tr> | ||
[[ | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/RAPA_ECO45 RAPA_ECO45]] Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Gan, J]] | [[Category: Gan, J]] | ||
[[Category: Ji, X]] | [[Category: Ji, X]] | ||
[[Category: Jin, D | [[Category: Jin, D J]] | ||
[[Category: Joachimiak, A]] | [[Category: Joachimiak, A]] | ||
[[Category: Shaw, G X]] | |||
[[Category: Zhang, R]] | |||
[[Category: Zhou, Y N]] | |||
[[Category: Hydrolase]] | |||
[[Category: Transcription]] | |||
Revision as of 09:50, 13 December 2017
Crystal structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcriptionCrystal structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription
Structural highlights
Function[RAPA_ECO45] Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair. |
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