4xe2: Difference between revisions

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==N-terminal domain of Hsp90 from Dictyostelium discoideum in complex with peptide==
==N-terminal domain of Hsp90 from Dictyostelium discoideum in complex with peptide==
<StructureSection load='4xe2' size='340' side='right' caption='[[4xe2]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
<StructureSection load='4xe2' size='340' side='right'caption='[[4xe2]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4xe2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_11735 Atcc 11735]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XE2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XE2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4xe2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XE2 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hspD, hsc90, hsp90, DDB_G0267400 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=44689 ATCC 11735])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xe2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xe2 OCA], [https://pdbe.org/4xe2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xe2 RCSB], [https://www.ebi.ac.uk/pdbsum/4xe2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xe2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xe2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xe2 OCA], [http://pdbe.org/4xe2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xe2 RCSB], [http://www.ebi.ac.uk/pdbsum/4xe2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xe2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HSC90_DICDI HSC90_DICDI]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).  
[https://www.uniprot.org/uniprot/HSC90_DICDI HSC90_DICDI] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
<div class="pdbe-citations 4xe2" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4xe2" style="background-color:#fffaf0;"></div>
==See Also==
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 11735]]
[[Category: Dictyostelium discoideum]]
[[Category: Raman, S]]
[[Category: Large Structures]]
[[Category: Suguna, K]]
[[Category: Raman S]]
[[Category: Acp]]
[[Category: Suguna K]]
[[Category: Chaperone]]
[[Category: Hsp90]]

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